In rapidly progressive Glomerular Nephruty (RPGN) also known as Crecentric Glomerulonephritis is due to proliferation of parietal epithelium of glomerulus and thickening of Basement membrane.
Why is it always in Crecentric shape? I mean - "Why not like a ring"?
Maybe the answer lies in the Gaussian curve? All points in the 360 degree of glomerulus has an equal chance of being affected by the injurious stimulus , and once affected the proliferation peak is the maximum at the point of injury and decreases evenly as we move away from that point ?
Having said that, I haven't been able to find a case of Rapidly Progressive Glomerular Nephritis which is not Crecentric in shape.
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